Sirens and a round of explosions, possibly from Israeli interceptors, could be heard booming in the sky over Jerusalem early Saturday and the Israeli military said another attack was taking place.
The Israeli military urged civilians, already rattled by an earlier wave of missiles, to head to shelter.
The Iranian outlet Nour News, which has close links with the paramilitary Revolutionary Guard, said a wave was being launched.
Iran immediately announced it would establish a third enrichment site and install more advanced centrifuges.
Even so, there are multiple assessments on how many nuclear weapons Iran could conceivably build, should it choose to do so. Iran would need months to assemble, test and field any weapon, which it so far has said it has no desire to do.
US intelligence agencies also assess Iran does not have a weapons program at this time.
US Secretary of State Marco Rubio said Israel took “unilateral action against Iran” and that it believed the strikes were necessary for its self-defence.
The International Atomic Energy Agency said it was closely monitoring radiation levels.
